CD40L antibody (70R-13704)

Affinity purified Rabbit polyclonal CD40L antibody

Synonyms Polyclonal CD40L antibody, Anti-CD40L antibody, CDL-40 antibody, CDL-40, CDL 40 antibody, TNFSF5 antibody, T-BAM antibody, CDL 40, TRAP antibody, soluble CD40 Ligand antibody, CD40L, CD154 antibody, gp39 antibody
Applications IHC-P, WB
Immunogen CD40L antibody was raised in Rabbit using a synthetic peptide corresponding to a sequence at the N-terminal of human CD40L, different from the related Rabbit sequence by three amino acids, rat sequence by four amino acids, as the immunogen

Specifications

Host Rabbit
Isotype IgG
Method of Purification CD40L antibody was purified by affinity chromatography
Form & Buffer Supplied in lyophilized form

Usage & Assay Information

Usage Recommendations Optimal conditions to be determined by the end user

Storage & Safety

Storage Store at 4 deg C for short term storage. For long term storage aliquot and store at -20 deg C, avoid repeated freeze/thaw cycles.

General Information

Biological Significance CD40, a member of the TNF receptor family, is a cell surface protein expressed on B cells, dendritic cells, monocytes, thymic epithelial cells and, at low levels, on T cells. Signaling though CD40 plays an important role in the proliferation and differentiation of B cells, and is critical for immunoglobulin (Ig) class switching. The membrane-anchored CD40-Ligand is expressed almost exclusively on activated CD4+ T lymphocytes. Failure to express CD40L leads to "immunodeficiency with hyper-IgM", a disease characterized by failure to produce IgG, IgA and IgE. The human CD40L gene codes for a 261 amino acid type II transmembrane protein, which contains a 22 amino acid cytoplasmic domain, a 24 amino acid transmembrane domain, and a 215 amino acid extracellular domain.

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Availability: In stock

Price: €220.86
Size: 100 ug
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