CD40LG protein (His tag) (80R-1774)

Purified recombinant Human CD40LG protein

Synonyms CD-40LG, IGM protein, CD154 protein, TNFSF5 protein, CD40L protein, IMD3 protein, CD40 ligand protein, CD-40LG BLGocking Peptide, CD 40LG BLGocking Peptide, gp39; hCD40L protein, TRAP protein, CD40LG, CD 40LG, T-BAM protein, HIGM1 protein
Species Human
Protein Type Recombinant
Applications SDS-PAGE

Images

Coomassie Blue stained SDS-PAGE of CD40LG protein (His tag) (80R-1774)

Figure annotation denotes ug of protein loaded and % gel used.

Specifications

Residues 113-261 amino acids: MGSSHHHHHH SSGLVPRGSH MQKGDQNPQI AAHVISEASS KTTSVLQWAE KGYYTMSNNL VTLENGKQLT VKRQGLYYIY AQVTFCSNRE ASSQAPFIAS LCLKSPGRFE RILLRAANTH SSAKPCGQQS IHLGGVFELQ PGASVFVNVT DPSQVSHGTG FTSFGLLKL
Expression System E.coli
Grade & Purity > 95% pure
Molecular Weight 18.3 kDa (169aa), confirmed by MALDI-TOF
Tag/Conjugate His tag
Form & Buffer Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, containing 1mM DTT, 40% glycerol and 0.2M NaCl.
Concentration 0.5 mg/ml

Storage & Safety

Storage Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance CD40 ligand, also known as CD40LG, is a member of the TNF superfamily and is expressed on activated T cells. CD40LG is expressed as a soluble cytokine as well as a homotrimeric type II transmembrane protein. It has been reported to be important for B cell costimulation following binding of its receptor, CD40. Mutations in the gene encoding for CD154 are implicated in hyper-IgM immunodeficiency syndrome type 1. Recombinant human CD40LG protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

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Images

  • Coomassie Blue stained SDS-PAGE of CD40LG protein (His tag) (80R-1774) | Figure annotation denotes ug of protein loaded and % gel used.

Availability: In stock

Price: €239.92
Size: 100 ug
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