CD42d antibody (10R-6395)
Armenian Hamster monoclonal CD42d antibody
Overview
Overview
| Synonyms | Monoclonal CD42d antibody, Anti-CD42d antibody, GP5 antibody, GPV antibody, CD42d, CD-42d, CD 42d antibody, CD-42d antibody, CD 42d, platelet glycoprotein V antibody |
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| Specificity | Mouse, Rat |
| Applications | FC, Functional Assay, IHC |
| Assay Information | A test is defined as the amount (ug) of antibody that will stain a cell sample in a final volume of 100 ul. Cell number should be determined empirically but can range from 105 to 108 cells/test. It is recommended that the antibody be carefully titrated for optimal /formance in the assay of interest |
Images
Flow Cytometric analysis using CD42d antibody (10R-6395)
Staining of mouse platelets with CD41 antibody (FITC) and 0.125 ug of Armenian Hamster IgG Isotype Control (left) or 0.125 ug of CD42d antibody (right) followed by Anti-Armenian Hamster IgG (PE). Total events were used for analysis.
Specifications
| Host | Hamster |
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| Clone | 1C2 |
| Isotype | IgG |
| Method of Purification | CD42d antibody was purified by affinity chromatography. |
| Form & Buffer | Supplied in aqueous buffer with 0.09% sodium azide, may contain carrier protein/stabilizer. |
| Concentration | 500 ug/ml |
Usage & Assay Information
| Usage Recommendations | FC: = 1 ug/test |
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Storage & Safety
| Storage | Store at 2-8 deg C. Do not freeze. Protect from light. |
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General Information
| Biological Significance | The monoclonal antibody 1C2 recognizes mouse and rat CD42d, a single transmembrane protein also known as platelet glycoprotein V. CD42d interacts with CD42a, CD42b and CD42c to form the receptor for von willebrand factor and thrombin. This functional complex plays a role in platelet adhesion. Expression of CD42d is restricted to resting platelets and megakaryocytes and therefore is a good marker for development of megakaryocytes. |
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