CD43 antibody (10R-6398)

Mouse monoclonal CD43 antibody

Synonyms Monoclonal CD43 antibody, Anti-CD43 antibody, SPN antibody, gpL115 antibody, Leukosialin antibody, CD-43 antibody, CD 43 antibody, CD 43, CD-43, LSN antibody, CD43, Sialophorin antibody
Specificity Human
Applications FC, IHC
Assay Information A test is defined as the amount (ug) of antibody that will stain a cell sample in a final volume of 100 ul. Cell number should be determined empirically but can range from 105 to 108 cells/test. The HI98 antibody has also been tested by immunohistochemistry on FFPE tisue (IHC-P) at less than or equal to 10 ug/ml. It is recommended that the antibody be carefully titrated for optimal /formance in the assay of interest.

Specifications

Host Mouse
Clone 84-3C1
Isotype IgG1
Method of Purification CD43 antibody was purified by affinity chromatography.
Form & Buffer Supplied in aqueous buffer with 0.09% sodium azide, may contain carrier protein/stabilizer.
Concentration 500 ug/ml

Usage & Assay Information

Usage Recommendations FC: = 0.25 ug/test

Storage & Safety

Storage Store at 2-8 deg C. Do not freeze. Protect from light.

General Information

Biological Significance The monoclonal antibody 84-3C1 reacts with CD43, which is also known as leukosialin, galactoglycoprotein and sialophorin. CD43 is a sialomucin which like many mucins can have both adhesive and anti-adhesive functions. Expression of CD43 is found on most leukocytes except resting B lymphocytes. Proteolytic processing upon activation decreases surface expression. CD43 is involved in activation of T cells, B cells, NK cells, and monocytes. The counter-receptor for CD43 is CD169/SIGLEC-1, which is expressed on macrophages.

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Availability: In stock

Price: €122.70
Size: 100 ug
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