CD45 antibody (10R-1063)

Mouse monoclonal CD45 antibody

Synonyms Monoclonal CD45 antibody, Anti-CD45 antibody, receptor type antibody, L CA antibody, SCID due to PTPRC deficiency antibody, CD 45 antibody, protein tyrosine phosphatase antibody, CD45, T200 antibody, CD 45 antibody, CD45 antigen antibody, T200 glycoprotein antibody, C (PTPRC) antibody, LY5 antibody, Protein tyrosine phosphatase receptor type c polypeptide antibody, CD 45, GP180 antibody, CD-45 antibody, B220 antibody, CD-45, CD45 antibody, PTPRC antibody, Leukocyte common antigen antibody, Protein tyrosine phosphatase receptor type C antibody, LCA antibody
Specificity Human
Cross Reactivity To be determined by end-user.
Applications ELISA, WB
Immunogen CD45 antibody was raised in mouse using recombinant human CD45 (1029-1249aa) purified from E. coli as the immunogen.

Specifications

Host Mouse
Clone 3G4
Isotype IgG2a kappa
Source Anti-human CD45 antibody, clone 3G4, is derived from hybridization of mouse SP2/O myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human CD45 protein.
Method of Purification CD45 antibody was purified by protein-G affinity chromatography
Form & Buffer Supplied as a liquid in PBS, pH 7.4, with 0.1% NaN3.
Concentration 1 mg/ml

Usage & Assay Information

Usage Recommendations WB: 1:1,000-1:3,000

Storage & Safety

Storage Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance CD45 belongs to a family of heavily glycosylated, high molecular weight transmembrane glycoproteins expressed on all cells of haematopoietic origin. Structurally heterogeneous, CD45 consists of a family of eight isoforms ranging from 180,000 to 220,000 MW generated by alternative splicing of three exons differentially expressed on subpopulations of lymphocytes. CD45 protein tyrosine phosphatase activity plays a central role in T-cell activation. CD45 plays an important role in signal transduction inhibition or upregulation of various immunological functions,

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Availability: In stock

Price: €244.62
Size: 100 ul
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