Monoclonal CD55 antibody, Anti-CD55 antibody, CD-55, CD 55, DAF antibody, CD55, Decay accelerating factor antibody, CD 55 antibody, CD-55 antibody
Specificity
Human
Applications
FC, Functional Assay, IHC, IP, WB
Assay Information
A test is defined as the amount (ug) of antibody that will stain a cell sample in a final volume of 100 ul. Cell number should be determined empirically but can range from 105 to 108 cells/test. It is recommended that the antibody be carefully titrated for optimal /formance in the assay of interest
Store at 2-8 deg C. Do not freeze. Protect from light.
General Information
Biological Significance
The 143-30 monoclonal antibody reacts with human CD55, the 64-73 kDa molecule also known as DAF. CD55 is a GPI-anchored single chain glycoprotein expressed on all cells in contact with serum including all hematopoietic cells and vascular endothelium a soluble form of CD55 is also present in plasma and body fluids. CD55 is thought to play a role in the protection of cells from the damage by autologous complement via prevention of the amplification steps of the complement cascade. Antibodies against CD55 are mitogenic in the presence of phorbol esters.