CD5l protein (80R-4353)
Purified Recombinant CD5l protein (His tagged)
Overview
Overview
| Synonyms | CD5 antigen-like protein, Apoptosis inhibitory 6 protein, CT-2 protein, SP-alpha protein, AAC-11 protein |
|---|---|
| Species | Mouse |
| Protein Type | Recombinant |
| Applications | SDS-PAGE |
Specifications
| Residues | 22-352 aa: ESPTKVQLVG GAHRCEGRVE VEHNGQWGTV CDDGWDRRDV AVVCRELNCG AVIQTPRGAS YQPPASEQRV LIQGVDCNGT EDTLAQCELN YDVFDCSHEE DAGAQCENPD SDLLFIPEDV RLVDGPGHCQ GRVEVLHQSQ WSTVCKAGWN LQVSKVVCRQ LGCGRALLTY GSCNKSTQGK GPIWMGKMSC SGQEANLRSC LLSRLENNCT HGEDTWMECE DPFELKLVGG DTPCSGRLEV LHKGSWGSVC DDNWGEKEDQ VVCKQLGCGK SLHPSPKTRK IYGPGAGRIW LDDVNCSGKE QSLEFCRHRL WGYHDCTHKE DVEVICTDFD VLEHHHHHH |
|---|---|
| Expression System | Insect cells |
| Grade & Purity | > 95% pure |
| Molecular Weight | 37.6 kDa |
| Tag/Conjugate | His tag |
| Form & Buffer | Supplied in liquid form in Phosphate Buffered Saline (pH 7.4) containing 10% glycerol. |
| Concentration | 250 ug/ml |
Storage & Safety
| Storage | Store at 4 deg C short term (1-2 weeks). For long term storage, aliquot and store at -20 or -70 deg C. Avoid repeated freezing and thawing cycles. |
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| Endotoxin Levels | < 1.0 EU per 1 microgram of protein (determined by LAL method) |
General Information
| Biological Significance | CD5L, also known as CD5 antigen-like, plays a role in the regulation of the immune system. CD5L which is a secreted glycoprotein and expressed by macrophages presenting lymphoid tissues such as bone marrow, lymph node and thymus is up-regulated in macrophage at inflammatory sites. It sustains inflammatory reactions by both increasing the phagocytic capacity of macrophage and impeding the apoptosis of local macrophages, NK cells and T cells. |
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