CD7 antibody (FITC) (61R-1044)
Mouse monoclonal CD7 antibody (FITC)
Overview
Overview
| Synonyms | Monoclonal CD7 antibody, Anti-CD7 antibody, CD-7, CD7, CD 7 antibody, CD 7, CD-7 antibody, Leu-9 antibody |
|---|---|
| Specificity | Human |
| Applications | FC |
| Assay Information | A test is defined as the amount (ug)/test of antibody that will stain a cell sample in a final volume of 100 ul. Cell number should be determined empirically but can range from 105 to 108 cells/test. |
Images
Flow Cytometric analysis using CD7 antibody (FITC) (61R-1044)
Staining of normal human peripheral blood cells with CD4 antibody (PE) and Mouse IgG2a kappa Isotype Control (FITC) (left) or CD7 antibody (FITC) (right). Cells in the lymphocyte gate were used for analysis.
Specifications
| Host | Mouse |
|---|---|
| Clone | 4H9 |
| Isotype | IgG2a kappa |
| Tag/Conjugate | FITC |
| Form & Buffer | Supplied in aqueous buffer with 0.09% sodium azide, may contain carrier protein/stabilizer. |
| Concentration | 5 ul (0.125 ug)/test |
Usage & Assay Information
| Usage Recommendations | FC: 5 ul (0.125 ug)/test |
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Storage & Safety
| Storage | Store at 2-8 deg C. Do not freeze. Protect from light. |
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General Information
| Biological Significance | This 4H9 monoclonal antibody reacts with human CD7, a 40-kDa transmembrane glycoprotein belonging to the immunoglobulin superfamily. This molecule is expressed on peripheral blood T lymphocytes and natural killer cells, as well as on lymphoid and myeloid lineage precursors during adult hematopoiesis. Capable of providing a costimulatory signal and associating with CD3 and CD45, CD7 is involved in T cell activation. CD7 has also been detected on numerous T cell-derived leukemias and lymphomias. In fact, because CD7 expression is greater on CD4+ T cells in classical Hodgkin’s lymphoma than in benign reactive lymph adenopathy, this molecule may be used as a diagnostic for Hodgkin’s lymphoma.Blocking assays demonstrate that this clone recognizes the same epitope as clone 124-1D1. |
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