CD80 antibody (10R-7741)
Rat monoclonal CD80 antibody
Overview
Overview
| Synonyms | Monoclonal CD80 antibody, Anti-CD80 antibody, CD-80, CD-80 antibody, CD80, B71 antibody, CD 80, CD 80 antibody |
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| Specificity | Human CD80 |
| Applications | User optimized |
| Immunogen | CD80 antibody was raised in Rat using purified mouse LPS-activated B cells as the immunogen. |
Specifications
| Host | Rat |
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| Clone | mB7-1 |
| Isotype | IgG2a |
| Method of Purification | CD80 antibody was purified by Ion exchange chromatography |
| Form & Buffer | Supplied in lyophilized form, reconstitute in sterile H2O or PBS buffer |
Storage & Safety
| Storage | Store at 4 deg C for short term storage. For long term storage aliquot and store at -20 deg C, avoid repeated freeze/thaw cycles. |
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General Information
| Biological Significance | Cluster of Differentiation 80 (also CD80 and B7-1) is a protein found on activated B cells and monocytes that provides a costimulatory signal necessary for T cell activation and survival. It is the ligand for two different proteins on the T cell surface: CD28 (for autoregulation and intercellular association) and CTLA-4 (for attenuation of regulation and cellular disassociation). CD80 works in tandem with CD86 to prime T cells. |
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