CDC25A antibody (70R-14083)
Affinity purified Rabbit polyclonal CDC25A antibody
Overview
Overview
| Synonyms | Polyclonal CDC25A antibody, Anti-CDC25A antibody, CDCA 25, CDCA 25 antibody, CDC25A, CDCA-25 antibody, CDC25A2 antibody, cell division cycle 25 homolog A, S. pombe antibody, CDCA-25 |
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| Applications | IHC-P, WB |
| Immunogen | CDC25A antibody was raised in Rabbit using a synthetic peptide corresponding to a sequence at the N-terminal of human CDC25A, identical to the related rat and Rabbit sequence as the immunogen |
Images
Western blot analysis using CDC25A antibody (70R-14083)
Lane 1: A495 Cell Lysate, Lane 2: SMMC Cell Lysate, Lane 3: JURKAT Cell Lysate
Specifications
| Host | Rabbit |
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| Isotype | IgG |
| Method of Purification | CDC25A antibody was purified by affinity chromatography |
| Form & Buffer | Supplied in lyophilized form |
Usage & Assay Information
| Usage Recommendations | Optimal conditions to be determined by the end user |
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Storage & Safety
| Storage | Store at 4 deg C for short term storage. For long term storage aliquot and store at -20 deg C, avoid repeated freeze/thaw cycles. |
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General Information
| Biological Significance | CDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated. Two transcript variants encoding different isoforms have been found for this gene. |
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