CDC25B antibody (70R-14084)
Affinity purified Rabbit polyclonal CDC25B antibody
Overview
Overview
| Synonyms | Polyclonal CDC25B antibody, Anti-CDC25B antibody, CDC 25, CDC-25 antibody, Cell Division Cycle 25 Homolog B antibody, CDC 25 antibody, CDC25, CDC-25 |
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| Applications | IHC-P, WB |
| Immunogen | CDC25B antibody was raised in Rabbit using a synthetic peptide corresponding to a sequence at the C-terminal of human CDC25B, different from the relative Rabbit sequence by three amino acids as the immunogen |
Images
Immunohistochemical staining using CDC25B antibody (70R-14084)
Immunohistochemistry of paraffin-embedded section of Human Lung Cancer Tissue
Specifications
| Host | Rabbit |
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| Isotype | IgG |
| Method of Purification | CDC25B antibody was purified by affinity chromatography |
| Form & Buffer | Supplied in lyophilized form |
Usage & Assay Information
| Usage Recommendations | Optimal conditions to be determined by the end user |
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Storage & Safety
| Storage | Store at 4 deg C for short term storage. For long term storage aliquot and store at -20 deg C, avoid repeated freeze/thaw cycles. |
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General Information
| Biological Significance | CDC25B is a member of the CDC25 family of phosphatases. CDC25B activates the cyclin dependent kinase CDC2 by removing two phosphate groups and it is required for entry into mitosis. CDC25B shuttles between the nucleus and the cytoplasm due to nuclear localization and nuclear export signals. The protein is nuclear in the M and G1 phases of the cell cycle and moves to the cytoplasm during S and G2. CDC25B has oncogenic properties, although its role in tumor formation has not been determined. |
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