Cdc27 antibody (10-2491)
Mouse monoclonal Cdc27 antibody
Overview
Overview
| Synonyms | Monoclonal Cdc27 antibody, Anti-Cdc27 antibody, ANAPC3, anaphase promoting complex subunit 3, anaphase-promoting complex, protein 3, APC3, CDC27, CDC27 homolog, CDC27Hs, cell division cycle 27 homolog (S. cerevisiae), cell division cycle protein 27, Cell division cycle protein 27 homolog, D0S1430E, D17S978E, H-NUC, HNUC, nuc2 homolog antibody |
|---|---|
| Specificity | Human |
| Cross Reactivity | Mammalian, Xenopus laevis |
| Applications | ELISA, FC, IHC, IP, WB |
| Immunogen | Cdc27 antibody was raised in Mouse using A peptide corresponding to the C-terminal 10 residues of human cdc27 coupled to KLH as the immunogen |
Specifications
| Host | Mouse |
|---|---|
| Clone | AF 3.1 |
| Isotype | IgG2b |
| Method of Purification | Cdc27 antibody purified by affinity chromatography |
| Form & Buffer | Supplied as liquid in PBS with 0.02% sodium azide |
| Concentration | 1 mg/ml |
Storage & Safety
| Storage | Store as concentrated solution. Aliquot and store at -20 deg C or below. Avoid repeated freeze-thaw cycles. |
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General Information
| Biological Significance | Cdc27 is a component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins. |
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