CDC42 antibody (70R-13909)

Affinity purified Rabbit polyclonal CDC42 antibody

Synonyms Polyclonal CDC42 antibody, Anti-CDC42 antibody, CDC42Hs antibody, CDC-42 antibody, cell division cycle 42, 25kDa antibody, CDC 42 antibody, GTP binding protein, G25K antibody, CDC-42, CDC 42, CDC42
Applications IHC-P, WB
Immunogen CDC42 antibody was raised in Rabbit using a synthetic peptide corresponding to a sequence in the middle region of human CDC42, identical to the related Rabbit and rat sequence as the immunogen

Images

Immunohistochemical staining using CDC42 antibody (70R-13909)

Immunohistochemistry of paraffin-embedded section of Human Mammary Cancer Tissue

Specifications

Host Rabbit
Isotype IgG
Method of Purification CDC42 antibody was purified by affinity chromatography
Form & Buffer Supplied in lyophilized form

Usage & Assay Information

Usage Recommendations Optimal conditions to be determined by the end user

Storage & Safety

Storage Store at 4 deg C for short term storage. For long term storage aliquot and store at -20 deg C, avoid repeated freeze/thaw cycles.

General Information

Biological Significance CDC42 is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in multiple transcript variants.

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Images

  • <div><font face=Calibri size=2>Immunohistochemical staining using CDC42 antibody (70R-13909)</font></div>     | Immunohistochemistry of paraffin-embedded section of Human Mammary Cancer Tissue
  • <div><font face=Calibri size=2>Western Blot analysis using CDC42 antibody (70R-13909)</font></div>     | Lane 1: Recombinant Human CDC42 Protein 10ng, Lane 2: Recombinant Human CDC42 Protein 5ng; Lane 3: Recombinant Human CDC42 Protein 2.5ng

Availability: In stock

Price: €220.86
Size: 100 ug
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