CDK5 antibody (10R-7445)

Mouse monoclonal CDK5 antibody

Synonyms Monoclonal CDK5 antibody, Anti-CDK5 antibody, Cyclin dependent kinase 5 antibody, TPKII catalytic subunit antibody, Cell division protein kinase 5 antibody, Protein kinase CDK5 splicing antibody, Tau protein kinase II catalytic subunit antibody, CDK5, PSSALRE antibody, Crk6 antibody, Serine threonine protein kinase PSSALRE antibody, CDK-5, CDK 5, CDK 5 antibody, CDK-5 antibody
Cross Reactivity Human, Mouse, Rat
Applications ELISA, IP, WB
Immunogen CDK5 antibody was raised in Mouse using His-tagged recombinant human CDK5 protein purified from Baculovirus expressed insect cells as the immunogen.

Images

Western blot analysis using CDK5 antibody (10R-7445)

Specifications

Host Mouse
Clone 8A1
Isotype IgG2b kappa
Method of Purification CDK5 antibody was purified by affinity chromatography.
Form & Buffer Supplied in PBS buffer (without mg2+ and Ca2+), pH 7.4, 150mM NaCl and 50% glycerol.
Concentration 1 mg/ml

Usage & Assay Information

Usage Recommendations ELISA: WB: 1:1000-2000 IP 2 ul/400 ul cell lysates

Storage & Safety

Storage Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles..

General Information

Biological Significance Cyclin-dependent kinase-5 (CDK5) is a member of the cyclindependent kinase family of serine/threonine kinases. Its mRNA and protein are expressed in kidney, testes, and ovary. And Its activity is detected almost exclusively in brain extracts. Similar to other Cdks, monomeric Cdk5 displays no enzymatic activity, but Cdk5 is not activated by cyclins. Instead, Cdk5 activity requires association with one of two brain-specific regulatory subunits called p35 and p39. The two activators regulate the spatial and temporal expression of active Cdk5 to restrict its activity primarily to post-mitotic neurons.

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Images

  • Western blot analysis using CDK5 antibody (10R-7445) |

Availability: In stock

Price: €257.67
Size: 100 ul
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