CEA protein (in TRIS) (30-AC26)
Purified native Human CEA protein
Overview
Overview
| Synonyms | Carcinoembryonic Antigen protein |
|---|---|
| Species | Human |
| Protein Type | Native |
| Applications | ELISA |
Specifications
| Source | Purified human liver carcinoma |
|---|---|
| Grade & Purity | > 80% pure |
| Form & Buffer | Supplied in 20mM TRIS-HClwith0.05% NaN3. |
| Concentration | Batch dependent - please inquire should you have specific requirements |
Usage & Assay Information
| Usage Recommendations | Optimal conditions to be determined by end user |
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Storage & Safety
| Storage | Aliquot and store at -20 deg C. Avoid repeated freeze/thaw cycles |
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| Biohazard Information | This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product. |
General Information
| Biological Significance | Carcinoembryonic antigen (CEA) is a glycoprotein involved in cell adhesion. It is normally produced during fetal development, but the production of CEA stops before birth. Therefore, it is not usually present in the blood of healthy adults, although levels are raised in heavy smokers. CEA is a glycosyl phosphatidyl inositol (GPI)-cell surface anchored glycoprotein whose specialized sialofucosylated glycoforms serve as functional colon carcinoma L-selectin and E-selectin ligands, which may be critical to the metastatic dissemination of colon carcinoma cells. |
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