CEA protein (30C-CP1001P)
Partially purified Human CEA protein
Overview
Overview
| Synonyms | Carcinoembryonic antigen protein |
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| Species | Human |
| Protein Type | Native |
| Applications | Control |
Specifications
| Source | Human colon adenocarcinoma cell line |
|---|---|
| Grade & Purity | Partially pure |
| Form & Buffer | PBS, pH 7.4, with 0.1% NaN3. |
Usage & Assay Information
| Usage Recommendations | This partially purified product is recommended for use as a single analyte standard or control. |
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Storage & Safety
| Storage | Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
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| Biohazard Information | This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product. |
General Information
| Biological Significance | Carcinoembryonic antigen (CEA) is a glycoprotein involved in cell adhesion. It is normally produced during fetal development, but the production of CEA stops before birth. Therefore, it is not usually present in the blood of healthy adults, although levels are raised in heavy smokers. CEA is a glycosyl phosphatidyl inositol (GPI)-cell surface anchored glycoprotein whose specialized sialofucosylated glycoforms serve as functional colon carcinoma L-selectin and E-selectin ligands, which may be critical to the metastatic dissemination of colon carcinoma cells. |
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