CEA protein (30C-CP3012P)
Purified native Human CEA protein
Overview
Overview
| Synonyms | Carcinoembryonic antigen protein |
|---|---|
| Species | Human |
| Protein Type | Native |
| Applications | User optimized |
Specifications
| Source | Human liver |
|---|---|
| Grade & Purity | > 40% pure |
| Form & Buffer | 0.15M Na3PO4, pH 7.4, with 0.01% NaN3. |
| Concentration | Batch dependent - please inquire should you have specific requirements |
Storage & Safety
| Storage | Store at 4 DEG C. DO NOT FREEZE. |
|---|---|
| Biohazard Information | Donor samples were tested and found to be negative for HIV I/II, and HCV antibodies, and Hepatitis B surface antigen. Nonetheless caution should be used when handling this material as there is a margin of error in all tests. This product contains sodium |
General Information
| Biological Significance | Carcinoembryonic antigen (CEA) is a glycoprotein involved in cell adhesion. It is normally produced during fetal development, but the production of CEA stops before birth. Therefore, it is not usually present in the blood of healthy adults, although levels are raised in heavy smokers. CEA is a glycosyl phosphatidyl inositol (GPI)-cell surface anchored glycoprotein whose specialized sialofucosylated glycoforms serve as functional colon carcinoma L-selectin and E-selectin ligands, which may be critical to the metastatic dissemination of colon carcinoma cells. |
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