Ceruloplasmin antibody (10R-8442)
Mouse monoclonal Ceruloplasmin antibody
Overview
Overview
| Synonyms | Monoclonal Ceruloplasmin antibody, Anti-Ceruloplasmin antibody, CP antibody, ceruloplasmin (ferroxidase) antibody, CERP antibody, ceruloplasmin antibody, ceruloplasmin-like antibody, CH211-284E20.2 antibody, clipped antibody, CP-2 antibody, D3Ertd555e antibody, E(nd)88 antibody, FBgn0000354 antibody, ferroxidase antibody, fi23f10 antibody, hypothetical protein antibody, RATCERP antibody, RCJMB04_23k5 antibody |
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| Cross Reactivity | Human |
| Applications | ELISA, IHC-P, IP, WB |
| Immunogen | Ceruloplasmin antibody was raised in Mouse using a protein purified from Human plasma as the immunogen |
Specifications
| Host | Mouse |
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| Clone | 3B11 |
| Isotype | IgG1 kappa |
| Method of Purification | Ceruloplasmin antibody was purified by ammonium sulfate precipitation |
| Form & Buffer | Supplied in liquid form in HEPES buffer with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol |
Usage & Assay Information
| Usage Recommendations | WB: 1:1000, IP: 1 ul |
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Storage & Safety
| Storage | Aliquot and store for 1 year at -20 deg C, avoid freeze/thaw cycles |
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General Information
| Biological Significance | Ceruloplasmin, 132 kDa, is a serum ferroxidase that contains greater than 95% of the copper found in plasma. This protein is a member of the multicopper oxidase family, an evolutionarily conserved group of proteins that utilize copper to couple substrate oxidation with the four-electron reduction of oxygen to water. Despite the need for copper in ceruloplasmin function, this protein plays no essential role in the transport or metabolism of this metal. Serum ceruloplasmin level is reduced in Wilson's disease, malnutrition nephrotic syndrome and increased in pregnancy, oestrogen containing contraceptives, acute infection, some types of chronic liver disease, malignancy, rheumatoid arthritis. |
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