CFP10 protein (30-1354)

PurifiedRecombinant CFP10 protein

Synonyms ESAT-6-like protein, esxB protein, Secreted antigenic protein MTSA10, 10 kDa culture filtrate antigen, CFP-10, CFP 10
Species Mycobacterium tuberculosis
Protein Type Recombinant
Applications Calibrator, ELISA

Specifications

Source Mycobacterium tuberculosis
Grade & Purity > 90% pure
Form & Buffer Liquid,dissolved in 20 mM Tris-HCl, 500 mM NaCl, pH 8.0, 50% glycerol

Storage & Safety

Storage Aliquot and store at -20 or -80 deg C. Avoid repeated freeze/thaw cycles

General Information

Biological Significance CFP10 is an antigen that contributes to the virulence Mycobacterium tuberculosis. CFP-10 forms a tight 1:1 heterodimeric complex with 6kDaA early secreted antigen target (ESAT-6). In the mycobacterial cell, these two proteins are interdependent on each other for stability. The ESAT-6/CFP-10 complex is secreted by the ESX-1 secretion system, also known as the RD1 region. The RD1 region is genomic and is present in all strains of Mycobacterium tuberculosis. Mycobacterium tuberculosis uses this ESX-1 secretion system to deliver virulence factors into host macrophage and monocyte white blood cells during infection.

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Availability: In stock

Price: €265.85
Size: 250 ug
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