CFTR antibody (10R-C123a)

Mouse monoclonal CFTR antibody

Synonyms Monoclonal CFTR antibody, Anti-CFTR antibody, Cystic Fibrosis Transmembrane Conductance Regulator antibody
Specificity Human
Cross Reactivity To be determined by end-user
Applications ICC, IP, WB
Immunogen CFTR antibody was raised in mouse using a synthetic peptide(RKGYRQRLELSD) corresponding to residues 25-36 of human cystic fibrosis transmembrane conductance regulator (CFTR) as the immunogen.

Images

Western blot analysis using CFTR antibody (10R-C123a)

Western Blot Analysis: T84 cell lysate was resolved by electrophoresis, transferred to nitrocellulose and probed with anti- CFTR (0.5 ug/mL). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and a chemiluminescence detection system. Arrow indicates CFTR (~170 kDa)

Specifications

Host Mouse
Clone MM13-4
Isotype IgG1 kappa
Method of Purification CFTR antibody was purified by Protein A chromatography.
Molecular Weight 170 kDa (predicted detection band MW)
Form & Buffer Protein G purified antibody supplied in 100mM Tris-glycine, pH 7.4, with 0.15M NaCl, and 0.05% NaN3.
Concentration Batch dependent - please inquire should you have specific requirements

Usage & Assay Information

Usage Recommendations Optimal conditions to be determined by end user

Storage & Safety

Storage Store at 4 deg C.
Biohazard Information This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling.

General Information

Biological Significance CFTR (Cystic Fibrosis Transmembrane conductance Regulator) is a 170 kDa chloride (Cl-) channel that regulates salt and water transport across epithelial tissues, where it modulates production of mucus, sweat, saliva, tears, and digestive enzymes. Cystic fibrosis patients have mutations in this protein, resulting in defective ion transport.

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Images

  • Western blot analysis using CFTR antibody (10R-C123a) | Western Blot Analysis: T84 cell lysate was resolved by electrophoresis, transferred to nitrocellulose and probed with anti- CFTR (0.5 ug/mL). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and a chemiluminescence detection system. Arrow indicates CFTR (~170 kDa)

Availability: In stock

Price: €522.17
Size: 200 ug
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