Chikungunya virus antibody (10-2716)
Mouse monoclonal Chikungunya virus envelope antibody
Overview
Overview
| Synonyms | Chikugunya E1 antibody, Chikugunya Envelope antibody, Chikugunya antibody, Monoclonal Chikungunya antibody, Chikungunya, CHIKV antibody |
|---|---|
| Specificity | Chikungunya envelope protein |
| Applications | Lateral Flow |
| Immunogen | Chikungunya antibody was raised in Mouse using a mixture of recombinant Chikungunya E1 wild type protein (cat # 30-1942) and recombinant Chikungunya E1 mutant (A226V) protein (cat # 30-1943) |
| Assay Information | Recombinant proteins 30-1943 and 30-1942 used as immuogens to raise this antibody are recommended for use as positive controls. |
Specifications
| Host | Mouse |
|---|---|
| Clone | M86677 |
| Isotype | IgG2b |
| Grade & Purity | > 90% pure |
| Method of Purification | Chikungunya antibody was purified by DEAE column chromatography |
| Form & Buffer | Supplied in liquid form in a 0.015M potassium phosphate buffer, 0.85% NaCl, pH 7.2 |
Storage & Safety
| Storage | Store at 2-8 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. |
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General Information
| Product Use | Development of lateral flow assays to detect Chikungunga virus |
|---|---|
| Biological Significance | Chikungunya virus is an insect-borne virus, of the genus Alphavirus, that is transmitted to humans by virus-carrying Aedes mosquitoes. There have been recent breakouts of CHIKV associated with severe illness. Outbreaks have occurred in countries in Africa, Asia, Europe, and the Indian and Pacific Oceans. In late 2013, chikungunya virus was found for the first time in the Americas on islands in the Caribbean. |
| Implications in Disease | CHIKV infection causes an illness with symptoms similar to dengue fever, with an acute febrile phase of the illness lasting only two to five days, followed by a prolonged arthralgic disease that affects the joints of the extremities. The pain associated with CHIKV infection of the joints persists for weeks or months, or in some cases years. There is no vaccine to prevent or medicine to treat chikungunya virus infection. |
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