Chitotriosidase antibody (70R-12593)

Affinity purified Rabbit polyclonal Chitotriosidase antibody

Synonyms Polyclonal Chitotriosidase antibody, Anti-Chitotriosidase antibody, CHI3 antibody, plasma methylumbelliferyl tetra-N-acetylchitotetraoside hydrolase antibody, chitinase-1 antibody, CHIT antibody, FLJ00314 antibody, CHIT1 antibody, MGC125322 antibody, chitotriosidase-1 antibody
Cross Reactivity Human
Applications WB
Immunogen Chitotriosidase antibody was raised in rabbit using a recombinant fragment corresponding to a region within amino acids 216 and 463 of Chitotriosidase

Images

Western blot analysis using Chitotriosidase antibody (70R-12593)

Western blot analysis of 30 ug of whole cell lysate (A: Hela) using a 10 % SDS PAGE gel and Chitotriosidase antibody at a dilution of 1:1000

Specifications

Host Rabbit
Isotype IgG
Method of Purification Chitotriosidase antibody was purified by antigen-affinity chromatography
Molecular Weight 52 kDa
Form & Buffer Supplied as a concentrated soloution containing 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH 7.0). 0.01% Thimerosal was added as a preservative.
Concentration 1 mg/ml

Usage & Assay Information

Usage Recommendations WB: 1:500-1:3000

Storage & Safety

Storage Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance Chitotriosidase is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens.

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Images

  • <div><font face=Calibri size=2>Western blot analysis using Chitotriosidase antibody (70R-12593)</font></div>     | Western blot analysis of 30 ug of whole cell lysate (A: Hela) using a 10 % SDS PAGE gel and Chitotriosidase antibody at a dilution of 1:1000

Availability: In stock

Price: €323.11
Size: 100 ul
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