Cholic acid-OVA (80-1427)
OVA conjugated Cholic acid Hapten
Overview
Overview
| Synonyms | Cholic acid-OVA antigen, Cholic acid-OVA Hapten conjugate, Cholic acid OVA, 3a 7a 12a-trihydroxy-5B-cholan-24-oic acid hapten, Cholate hapten |
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| Protein Type | Synthetic |
| Applications | ELISA, IHC |
Specifications
| Method of Purification | Cholic acid-OVA was purified by dialysis |
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| Tag/Conjugate | OVA |
| Form & Buffer | Supplied in lyophilized form in PBS buffer, pH 7.4 |
| Concentration | 0.01 mol/L |
Storage & Safety
| Storage | Store at 4 deg C for short term storage. For long term storage store at -20 deg C. Avoid repeated freeze/thaw cycles |
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General Information
| Biological Significance | Cholic acid downregulates cholesterol-7-a-hydroxylase (rate-limiting step in bile acid synthesis), and cholesterol does the opposite. This is why chenodeoxycholic acid, and not cholic acid, can be used to treat gallstones (because decreasing bile acid synthesis would supersaturate the stones even more). |
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