Cilastatin Ammonium Salt (powder) (51R-U134051)
Cilastatin Ammonium Salt chemical reference substance
|Form & Buffer||Supplied as a powder.|
|Biological Significance||Cilastatin is a chemical compound which inhibits the human enzyme dehydropeptidase. Dehydropeptidase is found in the kidney and is responsible for degrading the antibiotic imipenem. Cilastatin is therefore combined intravenously with imipenem in order to protect it from dehydropeptidase and prolong its antibacterial effect. However, cilastatin itself does not have antibiotic activity.|
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