Cingulin antibody (20R-2594)

Guinea Pig polyclonal Cingulin antibody

Synonyms Polyclonal Cingulin antibody, Anti Cingulin antibody
Specificity Human Cingulin
Cross Reactivity Bovine, Mouse, Rabbit, Fish
Applications IF, IHC, WB
Immunogen Cingulin antibody was raised in Guinea Pig using Full length GST-fusion protein of human cingulin as the immunogen.

Specifications

Host Guinea Pig
Form & Buffer Supplied in liquid form. Contains 0.09% sodium azide

Usage & Assay Information

Usage Recommendations IF: 1:100

Storage & Safety

Storage Store at 2-8 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance Cingulin is a protein that in humans is encoded by the CGN gene. Cingulin is specifically localized at tight junctions in epithelial cells, unlike ZO-1, which is also detected at adherens-type junctions in non-epithelial cells. During early Xenopus embryo development, cingulin is detected at a cortical localization, and then accumulates at apical junctions, unlike ZO-1 and other junctional proteins, that are targeted to the new regions of cell-cell contact via the lateral domain.

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