CINP protein (His tag) (80R-1876)
Purified recombinant CINP protein
|Synonyms||CDK2-interacting protein protein|
Coomassie Blue stained SDS-PAGE of CINP protein (His tag) (80R-1876)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||1-212 amino acids: MGSSHHHHHH SSGLVPRGSH MEAKTLGTVT PRKPVLSVSA RKIKDNAADW HNLILKWETL NDAGFTTANN IANLKISLLN KDKIELDSSS PASKENEEKV CLEYNEELEK LCEELQATLD GLTKIQVKME KLSSTTKGIC ELENYHYGEE SKRPPLFHTW PTTHFYEVSH KLLEMYRKEL LLKRTVAKEL AHTGDPDLTL SYLSMWLHQP YVESDSRLHL ESMLLETGHR AL|
|Grade & Purity||> 95% pure|
|Molecular Weight||26.4 kDa (232aa), confirmed by MALDI-TOF(Molecular weight on SDS-PAGE will appear higher)|
|Form & Buffer||Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, containing 20% glycerol, 0.1M NaCl and 1mM DTT.|
Storage & Safety
|Storage||Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||CINP, also known as Cyclin-dependent kinase 2-interacting protein, belongs to the CINP family. This protein interacts with the components of the replication complex and 2 kinases, CDK2 and CDC7, thereby providing a functional and physical link between CDK2 and CDC7 during firing of the origins of replication. Recombinant human CINP protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.|
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