Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.
Biohazard Information
This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product.
General Information
Biological Significance
The casein kinase 1 (CK1) family of protein kinases is common to all eukaryotic cells, with at least 15 sequence-distinct isoforms currently known. Although the isoforms differ in tissue distribution and subcellular localization, CK1 kinases share several characteristics in that they exhibit Ser/Thr-specific protein kinase activity. CK1-Delta has been implicated in the regulation of the tumor suppressor p53 and binds to microtubules, which suggests a regulatory role in mitosis.