CKBB antibody (20C-CR3012GP)
Goat polyclonal CKBB antibody
Overview
Overview
| Synonyms | Polyclonal CKBB antibody, Anti-CKBB antibody, CK BB antibody, CKBB antibody, Creatine Kinase BB Isoenzyme antibody |
|---|---|
| Specificity | Specific for human CK-BB |
| Cross Reactivity | 50% crossreaction with CK-MB |
| Applications | User optimized |
| Immunogen | CKBB antibody was raised in goat using purified human brain CKBB as the immunogen. |
Specifications
| Host | Goat |
|---|---|
| Form & Buffer | IgG fraction supplied in PBS, pH 7.4, 0.05% NaN3. |
| Concentration | Typically 4-6 mg/ml |
Storage & Safety
| Storage | Store at 4 DEG C for short term storage. Aliquot and store at -20 DEG C for long term storage. Avoid repeated freeze/thaw cycles. |
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| Biohazard Information | This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product. |
General Information
| Biological Significance | In the cells, the "cytosolic" creatine kinase (CK) enzymes consist of two subunits, which can be either B (brain type) or M (muscle type). There are, therefore, three different isoenzymes: CK-MM, CK-BB and CK-MB. The genes for these subunits are located on different chromosomes: B on 14q32 and M on 19q13. In addition to those three cytosolic CK isoforms, there are two mitochondrial creatine kinase isoenzymes, the ubiquitous and sarcomeric form. |
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