CKS2 protein (T7 tag) (80R-1070)
Purified recombinant Human CKS2 protein (T7 tag)
Overview
Overview
| Synonyms | CKS 2, CKS 2 protein, Cyclin-dependent kinases regulatory subunit 2 CDC28 protein kinase regulatory subunit 2 protein, CKSHS2 protein, CKS2, cerevisiae Cdc28/Cdc2 kinase subunit) homolog 2 protein, CKS-2, Cyclin-dependent kinases regulatory subunit 2 protein, CKS 2 protein, Cyclin dependent kinases regulatory subunit 2., CDC28 Protein kinase 2 protein, CKS1(S protein, CKS-2 protein, CKS2 protein |
|---|---|
| Species | Human |
| Protein Type | Recombinant |
| Applications | SDS-PAGE |
Images
Coomassie Blue stained SDS-PAGE of CKS2 protein (T7 tag) (80R-1070)
Figure annotation denotes ug of protein loaded and % gel used.
Specifications
| Residues | 1-79 amino acids: MASMTGGQQM GRGSHMAHKQ IYYSDKYFDE HYEYRHVMLP RELSKQVPKT HLMSEEEWRR LGVQQSLGWV HYMIHEPEPH ILLFRRPLPK DQQK |
|---|---|
| Expression System | E.coli |
| Grade & Purity | > 95% pure |
| Molecular Weight | 11.3 kDa (94aa), confirmed by MALDI-TOF. |
| Tag/Conjugate | T7 tag |
| Form & Buffer | Supplied as a liquid in PBS, pH 7.4, containing 40% glycerol, 2mM DTT, 0.1mM PMSF, and 1mM EDTA. |
| Concentration | 1 mg/ml |
Storage & Safety
| Storage | Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
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General Information
| Biological Significance | CKS2, also known as CDC28 Protein kinase 2 associates with the catalytic subunit of cyclin-dependent kinases and has therefore been assumed to play a direct role in cell cycle regulation. The function of CKS2 in somatic mammalian cells is not well understood although it is required for the first metaphase/anaphase transition during the meiosis. Emerging evidence shows that elevated expression of CKS2 protects the cells from apoptosis. Recombinant CKS2 fused with T7-tag was expressed in E. coli and purified by conventional chromatography techniques. |
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