CLEC9A antibody (10-2497)
Rat monoclonal CLEC9A antibody
Overview
Overview
| Synonyms | Monoclonal CLEC9A antibody, Anti-CLEC9A antibody, C-type lectin domain family 9 member A, C-type lectin domain family 9, member A, CLC9A, CLEC9A, DNGR1, HEEE9341, UNQ9341 antibody |
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| Specificity | Mouse |
| Applications | FC, IF, WB |
| Immunogen | CLEC9A antibody was raised in Rat using RBL-2H3 cells expressing mouse DNGR-1 fused to an HA epitope as the immunogen |
Specifications
| Host | Rat |
|---|---|
| Clone | 1F6 |
| Isotype | IgG1 |
| Method of Purification | CLEC9A antibody purified by affinity chromatography |
| Form & Buffer | Supplied as liquid in PBS with 0.02% sodium azide |
| Concentration | 1 mg/ml |
Storage & Safety
| Storage | Store as concentrated solution. Aliquot and store at -20 deg C or below. Avoid repeated freeze-thaw cycles. |
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General Information
| Biological Significance | CLEC9A functions as an endocytic receptor on a small subset of myeloid cells and induces intracellular signaling via spleen tyrosine kinase (Syk). Acts as a receptor for necrotic cells and can mediate the cross-presentation of dead-cell associated antigens in a Syk-dependent manner. |
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