CMPK1 protein (His tag) (80R-1740)

Purified recombinant Human CMPK1 protein

Synonyms CMPK-1, UMK protein, UMP-CMPK protein, CMK protein, CMPK-1 protein, UMP-CMP kinase protein, CMPK protein, UMPK protein, CMPK 1, RP11-511I2.1 protein, CMPK1, CMPK 1 protein
Species Human
Protein Type Recombinant
Applications SDS-PAGE

Images

Coomassie Blue stained SDS-PAGE of CMPK1 protein (His tag) (80R-1740)

Figure annotation denotes ug of protein loaded and % gel used.

Specifications

Residues 1-228 amino acids: MGSSHHHHHH SSGLVPRGSH MLSRCRSGLL HVLGLSFLLQ TRRPILLCSP RLMKPLVVFV LGGPGAGKGT QCARIVEKYG YTHLSAGELL RDERKNPDSQ YGELIEKYIK EGKIVPVEIT ISLLKREMDQ TMAANAQKNK FLIDGFPRNQ DNLQGWNKTM DGKADVSFVL FFDCNNEICI ERCLERGKSS GRSDDNRESL EKRIQTYLQS TKPIIDLYEE MGKVKKIDAS KSVDEVFDEV VQIFDKEG
Expression System E.coli
Grade & Purity > 90% pure
Molecular Weight 28.0 kDa (248aa), confirmed by MALDI-TOF
Tag/Conjugate His tag
Form & Buffer Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, containing 20% glycerol, 1mM DTT and 100mM NaCl.
Concentration 1 mg/ml

Storage & Safety

Storage Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance CMPK1, also known as UMP-CMP kinase and deoxycytidylate kinase, is an enzyme that catalyzes the phosphoryl transfer from ATP to UMP, CMP and dCMP. This enzymatic reaction leads to the formation of ADP and the corresponding nucleoside diphosphate, which are required for cellular nucleic acid synthesis. It also plays an important role in the activation of pyrimidine analogs, which are clinically useful anti-cancer and anti-viral drugs. Recombinant human CMPK1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.

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Images

  • Coomassie Blue stained SDS-PAGE of CMPK1 protein (His tag) (80R-1740) | Figure annotation denotes ug of protein loaded and % gel used.

Availability: In stock

Price: €319.89
Size: 100 ug
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