CMV Cell Lysate (35-1867)
CMV enriched cell lysate
Overview
Overview
| Synonyms | CMV antigen, Cytomegalovirus cell lysate antigen, Cytomegalovirus protein |
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| Species | Viral |
| Protein Type | Native |
Specifications
| Source | A clarified cell lysate containing a mix of CMV antigens |
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| Form & Buffer | Supplied in 0.5% Triton X-100 in PBS |
Storage & Safety
| Storage | Store at -80 deg C |
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General Information
| Product Use | CMV Cell Lysate can be used as a positive control in a broad range of immunoassays including western blotting and ELISA. |
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| Biological Significance | Cytomegalovirus is a genus of viruses in the order Herpesvirales, in the family Herpesviridae, in the subfamily Betaherpesvirinae. Human and monkeys serve as natural hosts. There are currently eight species in this genus including the type species human herpesvirus 5. Diseases associated with HHV-5 include mononucleosis, and pneumonias. |
| Implications in Disease | Most people infected with CMV who are otherwise healthy experience few if any symptoms. When first infected, some adults may have symptoms similar to mononucleosis, including fatigue, fever and muscle aches. An illness resembling infectious mononucleosis is the most common presentation of CMV in people with weakened immune systems (immunocompromised). CMV also can attack specific organs. Signs and symptoms may include: Fever, Pneumonia, Diarrhea, Ulcers in the digestive tract, Hepatitis, Inflammation of the brain (encephalitis), Behavioral changes, Seizures, Coma, Visual impairment and blindness. Newborns infected with CMV in the womb (congenital CMV), babies who become infected during birth or shortly after birth (perinatal CMV) such as through breast-feeding and people with weakened immune systems are more at risk of developing signs and symptoms than are healthy adults. |
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