cMyc antibody (10R-7845)

Mouse monoclonal cMyc antibody

Synonyms Monoclonal cMyc antibody, Anti-cMyc antibody, Myc antibody, Myc tag antibody
Applications ICC, IHC-P, WB
Immunogen cMyc antibody was raised in mouse using synthetic peptide corresponding to residues 408-439 of the human p62c-Myc protein as the immunogen

Images

Immunohistochemical staining using cMyc antibody (10R-7845)

Immunohistochemistry of paraffin embedded section of Rat Cardiac Muscle Tissue

Specifications

Host Mouse
Clone IMD-3
Isotype IgG2a
Form & Buffer Supplied in lyophilized form

Usage & Assay Information

Usage Recommendations Optimal conditions to be determined by the end user

Storage & Safety

Storage Store at 4 deg C for short term storage. For long term storage aliquot and store at -20 deg C, avoid repeated freeze/thaw cycles.

General Information

Biological Significance cMyc is an oncogene that functions both in the stimulation of cell proliferation and in apoptosis. c-Myc elicits its oncogenic activity by causing immortalization, and to a lesser extent the transformation of cells, in addition to several other mechanisms. The c-MYC proto-oncogene encodes a transcription factor that is critical for cell growth and proliferation. It is one of the genes frequently altered in cancer cells in which it exhibits constitutive activity. Downregulation of c-Myc is critical for 2-Methoxyestradiol (2ME2)-induced oxidative stress and apoptosis in AML cells. And its up-regulation is important for promoting lymphocyte cell division, and demonstrating that GFP-c-Myc expression is a marker of proliferating lymphocytes in vivo.

References
Add a Paper

Sorry, but there are no references currently for this product.

Reviews

You need to be logged in to write a review. Please login here

Sorry there are currently no reviews for this product

Images

  • Immunohistochemical staining using cMyc antibody (10R-7845) | Immunohistochemistry of paraffin embedded section of Rat Cardiac Muscle Tissue

Availability: In stock

Price: €208.59
Size: 100 ug
OR
Shipping
View Our Distributors