CNBP protein (His tag) (80R-2682)
Purified recombinant CNBP protein (His tag)
|Synonyms||Cellular nucleic acid-binding protein protein, CNBP1 protein, DM2 protein, PROMM protein, RNF163 protein, ZCCHC22 protein, ZNF9 protein, CNBP|
SDS-PAGE analysis of CNBP protein (His tag) (80R-2682)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||1-170 aa: MGSSHHHHHH SSGLVPRGSH MGSMSSNECF KCGRSGHWAR ECPTGGGRGR GMRSRGRGFQ FVSSSLPDIC YRCGESGHLA KDCDLQEDAC YNCGRGGHIA KDCKEPKRER EQCCYNCGKP GHLARDCDHA DEQKCYSCGE FGHIQKDCTK VKCYRCGETG HVAINCSKTS EVNCYRCGES GHLARECTIE ATA|
|Grade & Purity||> 90% pure|
|Molecular Weight||21 kDa|
|Form & Buffer||Supplied in liquid form in 20mM Tris-HCl buffer (pH 7.5) containing 0.2M NaCl, 20% glycerol, 1mM DTT.|
Storage & Safety
|Storage||Can be stored at 4 deg C for short terms (1-2 weeks). For long term storage, aliquot and store at -20 deg C or -70 deg C. Avoid repeated freezing and thawing cycles|
|Biological Significance||CNBP is a nucleic-acid binding protein with seven zinc-finger domains. The protein has a preference for binding single stranded DNA and RNA. It functions in cap-independent translation of ornithine decarboxylase mRNA, and may also function in sterol-mediated transcriptional regulation. A CCTG expansion in the first intron of this gene results in myotonic dystrophy type 2. Recombinant human CNBP protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.|
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