CNTF protein (30R-2431)

Purified recombinant Rat CNTF protein

Synonyms CNTF protein, Ciliary Neurotrophic Factor protein, HCNTF protein
Species Rat
Protein Type Recombinant

Specifications

Expression System E.coli
Method of Purification CNTF protein was purified using a a proprietary chromatographic technique.
Molecular Weight 22.834 kDa
Form & Buffer Supplied in lyophilized form from 0.025% NaHCO3

Storage & Safety

Storage Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance CNTF is a polypeptide hormone whose actions appear to be restricted to the nervous system where it promotes neurotransmitter synthesis and neurite outgrowth in certain neuronal populations. The protein is a potent survival factor for neurons and oligodendrocytes and may be relevant in reducing tissue destruction during inflammatory attacks. A mutation in this gene, which results in aberrant splicing, leads to ciliary neurotrophic factor deficiency, but this phenotype is not causally related to neurologic disease. CNTF is a survival factor for various neuronal cell types and seems to prevent the degeneration of motor axons after axotomy.

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Availability: In stock

Price: €224.95
Size: 20 ug
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