CNTF protein (80R-4366)

Purified Recombinant CNTF protein (His tagged)

Synonyms Ciliary neurotrophic factor protein, HCNTF protein
Species Rat
Protein Type Recombinant
Applications SDS-PAGE

Images

SDS-PAGE analysis using CNTF protein (His tag) (80R-4366)

Specifications

Residues 1-200 aa: MGSSHHHHHH SSGLVPRGSH MGSMAFAEQT PLTLHRRDLC SRSIWLARKI RSDLTALMES YVKHQGLNKN INLDSVDGVP VASTDRWSEM TEAERLQENL QAYRTFQGML TKLLEDQRVH FTPTEGDFHQ AIHTLMLQVS AFAYQLEELM VLLEQKIPEN EADGMPATVG DGGLFEKKLW GLKVLQELSQ WTVRSIHDLR VISSHQMGIS ALESHYGAKD KQM
Expression System E.coli
Grade & Purity > 95% pure
Molecular Weight 25.2 kDa
Tag/Conjugate His tag
Form & Buffer Supplied in liquid form in phosphate buffered saline (pH 7.4) containing 10% glycerol.
Concentration 500 ug/ml

Storage & Safety

Storage Store at 4 deg C short term (1-2 weeks). For long term storage, aliquot and store at -20 or -70 deg C. Avoid repeated freezing and thawing cycles.
Endotoxin Levels < 1.0 EU per 1 microgram of protein (determined by LAL method)

General Information

Biological Significance CNTF also known as ciliary neurotrphic factor is a survival factor for various neuronal cell types. CNTF is highly conserved across species and exhibits cross-species bioactivity. CNTF is a 25 kDa polypeptide that was originally isolated as a target-derived survival factor of parasympathetic ciliary ganglion neurons. Binding of CNTF to CNTF receptor triggers heterodimerization of gp130 and LIFR, forming an active trimeric receptor complex and activates the downstream signaling pathway.

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Images

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SDS-PAGE analysis using CNTF protein (His tag) (80R-4366)



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Availability: In stock

Price: €300.20
Size: 50 ug
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