CNTF protein (80R-4366)
Purified Recombinant CNTF protein (His tagged)
Overview
Overview
| Synonyms | Ciliary neurotrophic factor protein, HCNTF protein |
|---|---|
| Species | Rat |
| Protein Type | Recombinant |
| Applications | SDS-PAGE |
Specifications
| Residues | 1-200 aa: MGSSHHHHHH SSGLVPRGSH MGSMAFAEQT PLTLHRRDLC SRSIWLARKI RSDLTALMES YVKHQGLNKN INLDSVDGVP VASTDRWSEM TEAERLQENL QAYRTFQGML TKLLEDQRVH FTPTEGDFHQ AIHTLMLQVS AFAYQLEELM VLLEQKIPEN EADGMPATVG DGGLFEKKLW GLKVLQELSQ WTVRSIHDLR VISSHQMGIS ALESHYGAKD KQM |
|---|---|
| Expression System | E.coli |
| Grade & Purity | > 95% pure |
| Molecular Weight | 25.2 kDa |
| Tag/Conjugate | His tag |
| Form & Buffer | Supplied in liquid form in phosphate buffered saline (pH 7.4) containing 10% glycerol. |
| Concentration | 500 ug/ml |
Storage & Safety
| Storage | Store at 4 deg C short term (1-2 weeks). For long term storage, aliquot and store at -20 or -70 deg C. Avoid repeated freezing and thawing cycles. |
|---|---|
| Endotoxin Levels | < 1.0 EU per 1 microgram of protein (determined by LAL method) |
General Information
| Biological Significance | CNTF also known as ciliary neurotrphic factor is a survival factor for various neuronal cell types. CNTF is highly conserved across species and exhibits cross-species bioactivity. CNTF is a 25 kDa polypeptide that was originally isolated as a target-derived survival factor of parasympathetic ciliary ganglion neurons. Binding of CNTF to CNTF receptor triggers heterodimerization of gp130 and LIFR, forming an active trimeric receptor complex and activates the downstream signaling pathway. |
|---|
Reviews
You need to be logged in to write a review. Please login here
Sorry there are currently no reviews for this product