Collagen Type IV antibody (10R-C137b)

Mouse monoclonal Collagen Type IV antibody

Synonyms Monoclonal Collagen Type IV antibody, Anti-Collagen Type IV antibody, Collagen IV antibody, Collagen Type IV antibody
Specificity Human
Cross Reactivity To be determined by end-user
Applications IHC-F, IHC-P
Immunogen Collagen type IV antibody was raised in mouse using human glomeruli as the immunogen.

Images

Immunohistochemical staining using Collagen Type IV antibody (10R-C137b)

Formalin-fixed, paraffin-embedded human skin stained with Collagen IV antibody using peroxidase-conjugate and DAB chromogen. Note basement membrane staining of sweat glands, blood vessels and nerves.

Specifications

Host Mouse
Clone PHM-12, CIV 22
Isotype IgG1
Form & Buffer Tissue culture supernatant with 0.09% NaN3.
Concentration Batch dependent - please inquire should you have specific requirements

Usage & Assay Information

Usage Recommendations IHC-F: 1:50-1:100, IHC-P: 1:50-1:100

Storage & Safety

Storage Store at 4 deg C.
Biohazard Information This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling.

General Information

Biological Significance Collagen IV is a major constituent of the basement membranes along with laminins and enactins. It is composed of alpha1(IV) chain and alpha2(IV) chain in 2:1 ratio . It can form insoluble fibers with high tensile strength. Antibody to collagen IV is useful in detecting the loss of parts of basement membrane in carcinomas.

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Images

  • Immunohistochemical staining using Collagen Type IV antibody (10R-C137b) | Formalin-fixed, paraffin-embedded human skin stained with Collagen IV antibody using peroxidase-conjugate and DAB chromogen. Note basement membrane staining of sweat glands, blood vessels and nerves.

Availability: In stock

Price: €424.32
Size: 500 ul
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