COMMD1 protein (His tag) (80R-1392)

Purified recombinant Human COMMD1 protein

Synonyms MURR-1, C2orf5 protein, MURR1 protein, COMMD-1 protein, COMMD-1 protein, MURR 1 protein, COMMD1, COMM domain-containing protein 1 protein, COMMD-1, COMMD 1, COMMD 1 protein, COMM protein, COMMD 1 protein
Species Human
Protein Type Recombinant
Applications SDS-PAGE

Specifications

Residues 1-190 amino acids: MGSSHHHHHH SSGLVPRGSH MAAGELEGGK PLSGLLNALA QDTFHGYPGI TEELLRSQLY PEVPPEEFRP FLAKMRGILK SIASADMDFN QLEAFLTAQT KKQGGITSDQ AAVISKFWKS HKTKIRESLM NQSRWNSGLR GLSWRVDGKS QSRHSAQIHT PVAIIELELG KYGQESEFLC LEFDEVKVNQ ILKTLSEVEE SISTLISQPN
Expression System E.coli
Grade & Purity > 90% pure
Molecular Weight 23.3 kDa (210aa), confirmed by MALDI-TOF
Tag/Conjugate His tag
Form & Buffer Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, containing 20% glycerol and 0.1M NaCl.
Concentration 0.5 mg/ml

Storage & Safety

Storage Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance COMMD1, also known as copper metabolism MURR1 domain-containing protein 1, is a 190 amino acid protein responsible for inhibition of TNF-induced NFkB p50 and has a suggested role in facilitation of biliary copper excretion within hepatocytes. High expression is found in liver tissue, with lower expressions in lung, heart, kidney and brain tissue. This protein interacts directly with COMMD6 and ATP7B. Recombinant human COMMD1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

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Availability: In stock

Price: €319.89
Size: 50 ug
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