Complement C1 protein (32C-CP1093)
Purified Complement C1 protein isolated from human plasma
Overview
Overview
| Synonyms | C1 protein |
|---|---|
| Species | Human |
| Protein Type | Native |
Specifications
| Source | Human serum/plasma |
|---|---|
| Molecular Weight | 766 kDa |
| Form & Buffer | 0.2 um filtered frozen liquid in 50mM NaAcetate, 50mM EACA, 10mM Benzamidine, 10mM EDTA, 300mM NaCl and 40% Glycerol, pH 5.5, with no presveratives added. |
Usage & Assay Information
| Bioactivity | >250,000 C1H50 units/mg total protein |
|---|
Storage & Safety
| Storage | Aliquot and store at -70 deg C or lower. Avoid repeated freeze/thaw cycles. |
|---|---|
| Biohazard Information | Donor samples were tested and found to be negative for HBsAg, HTLV-I/II, STS, and for antibodies to HCV, HIV-1 and HIV-II. Nonetheless caution should be used when handling this material as there is a margin of error in all tests. |
General Information
| Biological Significance | C1 is the first complement component in the cascade referred to as the classical pathway of complement. C1 binds to and is activated by antibodies bound to antigens (immune complexes) yielding a protease that initiates the cascade. C1 is actually a non-covalent complex of three different proteins (C1q, C1r and C1s) bound together in a calcium-dependent complex. |
|---|
Reviews
You need to be logged in to write a review. Please login here
Sorry there are currently no reviews for this product