Complement C1q protein (32C-CP1002U)
Purified Complement C1q protein isolated from human plasma
Overview
Overview
| Synonyms | C1q protein |
|---|---|
| Species | Human |
| Protein Type | Native |
Specifications
| Source | Human serum/plasma |
|---|---|
| Grade & Purity | > 98% pure |
| Molecular Weight | 410 kDa |
| Form & Buffer | 40% Glycerol, 10mM HEPES, 300mM NaCl, pH 7.2. |
Usage & Assay Information
| Bioactivity | >1,000,000 C1H50 units/mg |
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Storage & Safety
| Storage | Aliquot and store at -70 deg C or lower. Avoid repeated freeze/thaw cycles. |
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| Biohazard Information | Donor samples were tested and found to be negative for HBsAg, HTLV-I/II, STS, and for antibodies to HCV, HIV-1 and HIV-II. Nonetheless caution should be used when handling this material as there is a margin of error in all tests. |
General Information
| Biological Significance | C1q is part of the C1 complex and this complex is the first complement component in the cascade referred to as the classical pathway of complement. C1 is actually a non-covalent assembly of three different proteins (C1q, C1r, and C1s) bound together in a calcium-dependent complex. C1q has six extended arms with domains at the end of each arm that bind to the Fc domains of immunoglobulins. |
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