Complement C3 antibody (10R-7447)

Mouse monoclonal Complement C3 antibody

Synonyms Monoclonal Complement C3 antibody, Anti-Complement C3 antibody, Complement C-3, Complement C 3 antibody, Complement C3, Complement C 3, Complement C-3 antibody, C3 antibody
Cross Reactivity Human
Applications ELISA, WB
Immunogen Complement C3 antibody was raised in Mouse using Complement C3 protein purified from Human plasma as the immunogen.

Images

Western blot analysis using Complement C3 antibody (10R-7447)

Specifications

Host Mouse
Clone 28A1
Isotype IgG2b kappa
Method of Purification Complement C3 antibody was purified by affinity chromatography.
Form & Buffer Supplied in PBS buffer (without mg2+ and Ca2+), pH 7.4, 150mM NaCl and 50% glycerol.
Concentration 1 mg/ml

Usage & Assay Information

Usage Recommendations WB: 1:500- 1000

Storage & Safety

Storage Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles..

General Information

Biological Significance Human Complement C3 (C3) is synthesized as a single-chain pro-molecule (185 kDa) that then suffers several posttranslational modifications. Before being secreted as a mature protein, C3 is split into beta-chain (645 residues and 70 kDa) and a chain (992 residues and 115 kDa) and forms a rare internal thioester bond. C3 plays a central role in the activation of all the three pathways of complement activation i.e. the classical, alternative, and lectin pathway. As C3 is the major complement component and participates in several stages of the immune response, its deficiency generally associated with higher susceptibility to severe bacterial infections and in some cases with autoimmune diseases such as systemic lupus erythematosus.

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Images

  • Western blot analysis using Complement C3 antibody (10R-7447) |

Availability: In stock

Price: €257.67
Size: 100 ul
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