Complement C3 antibody (20-S0503GND1-D0)
Goat polyclonal Human Complement C3 antibody
Overview
Overview
| Synonyms | Polyclonal Complement C3 antibody, Anti-Complement C3 antibody, Complement C3, Complement C-3, Complement C-3 antibody, Complement C 3 antibody, C3 antibody, Complement C 3 |
|---|---|
| Specificity | Human complement C3 |
| Applications | User optimized |
| Immunogen | Complement C3 antibody was raised in goat using complement C3 from normal human serum as the immunogen. |
Specifications
| Host | Goat |
|---|---|
| Form & Buffer | Supplied delipidated, defibrinated and 0.2um filtered, in 0.2M Tris, 0.5M NaCl , pH 7.6 with 0.09% NaN3 |
| Concentration | 3.12 mg/ml |
Storage & Safety
| Storage | Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
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General Information
| Biological Significance | Native human C3 is a naturally glycosylated (~2.7%) polypeptide containing two disulfide-linked chains. C3 is central to the activation of all three pathways of complement activation. Initiation of each pathway generates proteolytic enzyme complexes (C3 convertases) which are bound to the target surface. These enzymes cleave a peptide bond in C3 releasing the anaphylatoxin C3a and activating C3b. For a brief time (~60 us) this nascent C3b is capable of reacting with and covalently coupling to hydroxyl groups on the target surface. |
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