ODD: 5 uL antiserum vs 20 uL Fresh plasma, Immunodiffusion: 0.5 uL antiserum/cm^2 in gel vs 20 uL Fresh plasma, dilutions: Neat - 1:2.
Storage & Safety
Storage
Store at 4 deg C.
Biohazard Information
This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product.
General Information
Biological Significance
Complement component 4 is a protein involved in the complement system. It is cleaved into proteins 4a and 4b. C4a is an anaphylatoxin, C4b forms part of C3-convertase, in conjunction with 2a, C4b can bind CR1, and C4d is the final proteolytic remnant of deposited C4b on endothelium, remains covalently attached to endothelium for little more than a week and easily detectable by antibody staining.