Complement C4 protein (30-1087)

Purified native Human Complement C4 protein >95%

Synonyms Complement C-4 protein, Complement C-4, Complement C 4 protein, Complement C 4, Complement C4, C4 protein
Species Human
Protein Type Native

Specifications

Source Human Plasma
Grade & Purity > 95% pure
Form & Buffer Supplied in Sodium Phosphate buffer pH 7.0 containing 0.15M NaCl

Usage & Assay Information

Bioactivity > 800 units/mg at 37 deg C

Storage & Safety

Storage Ships on dry ice. Upon receipt store at -20 deg C

General Information

Biological Significance Component C4 interacts with C1 and C2 to form C3 convertase of the classic activation pathway. Systemic lupus erythematosus (SLE) is often associated with congenital C4 deficiency. Reduced levels of components of the classic pathway (C1, C2, C4, C3) are common after such activation, e.g. in SLE, acute serum sickness and conditions associated with circulating immune complexes. The common form present in plasma and used in diagnostics assays is the C4c form offered here.

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Availability: In stock

Price From: Price: €28.63
Price From: Price: €28.63
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