Complement C4 protein (32R-AC050-10)

Purified Complement C4 protein isolated from human plasma

Synonyms C4 protein
Species Human
Protein Type Native

Specifications

Source Human plasma
Grade & Purity > 99% pure
Molecular Weight 210 kDa
Form & Buffer Na3PO4 buffer, pH 7.0, with 150mM NaCl, and 0.09% NaN3.

Storage & Safety

Storage Aliquot and store at -20 deg C. Avoid repeated freeze/thaw cycles

General Information

Biological Significance Component C4 interacts with C1 and C2 to form C3 convertase of the classic activation pathway. Systemic lupus erythematosus (SLE) is often associated with congenital C4 deficiency. Reduced levels of components of the classic pathway (C1, C2, C4, C3) are common after such activation, e.g. in SLE, acute serum sickness and conditions associated with circulating immune complexes. The common form present in plasma and used in diagnostics assays is the C4c form offered here.

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Availability: In stock

Price: €1,500.66
Size: 10 mg
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