Complement C6 antibody (10R-8513)

Mouse monoclonal Complement C6 antibody

Synonyms Monoclonal Complement C6 antibody, Anti-Complement C6 antibody, C6 antibody, complement component 6 antibody, complement component C6 antibody, sixth complement component antibody
Cross Reactivity Human
Applications ELISA, IP, WB
Immunogen Complement C6 antibody was raised in Mouse using a protein purified from Human plasma as the immunogen

Images

Western Blot analysis using Complement C6 antibody (10R-8513)

Specifications

Host Mouse
Clone 13H5
Isotype IgG2b kappa
Method of Purification Complement C6 antibody was purified by ammonium sulfate precipitation
Form & Buffer Supplied in liquid form in HEPES buffer with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol

Usage & Assay Information

Usage Recommendations WB: 1:2000, IP: 2 ul

Storage & Safety

Storage Aliquot and store for 1 year at -20 deg C, avoid freeze/thaw cycles

General Information

Biological Significance The sixth component of complement, C6, is a 913 amino acid single polypeptide chain serum glycoprotein. Homology study suggests that C6 could contain two domains, an amino-terminal region that is related to complement C8 and C9, and a carboxyl-terminal region that has partial homology to the complement regulatory proteins factor H and factor I. Genetic deficiencies of terminal complement components lead to markedly increased susceptibility to only one particular Gram-negative genus, the Neisseria. The susceptibility is attributable to the major role played by complement-mediated killing in host defense against the pathogen.

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Images

  • Western Blot analysis using Complement C6 antibody (10R-8513)

Availability: In stock

Price: €241.31
Size: 100 ul
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