Complement C9 protein (32C-CP1050)

Purified Complement C9 protein isolated from human plasma

Synonyms C9 protein
Species Human
Protein Type Native

Specifications

Source Human serum/plasma
Grade & Purity > 95% pure
Molecular Weight 71 kDa
Form & Buffer Supplied as a liquid in PBS, pH 7.2, no preservatives added,

Storage & Safety

Storage Aliquot and store at -70 deg C or lower. Avoid repeated freeze/thaw cycles.
Biohazard Information Donor samples were tested and found to be negative for HBsAg, HTLV-I/II, STS, and for antibodies to HCV, HIV-1 and HIV-II. Nonetheless caution should be used when handling this material as there is a margin of error in all tests.

General Information

Biological Significance Native human C9 is a naturally glycosylated (7.8%) protein composed of a single polypeptide chain. The molecular weight is 71,000 Da. C9 binds to the C5b-8 complex and forms the mature membrane attack complex (MAC) on cell membranes. Each pathway of complement activation generates proteolytic enzyme complexes (C3/C5 convertases) which are bound to the target surface . These enzymes cleave a peptide bond in the larger alpha chain of C5 releasing the anaphylatoxin C5a and activating C5b.

References
Add a Paper

Sorry, but there are no references currently for this product.

Reviews

You need to be logged in to write a review. Please login here

Sorry there are currently no reviews for this product

Availability: In stock

Price: €348.87
Size: 250 ug
OR
Shipping
View Our Distributors