Complement factor H antibody (70R-12519)
Affinity purified Rabbit polyclonal Complement factor H antibody
Overview
Overview
| Synonyms | Polyclonal Complement factor H antibody, Anti-Complement factor H antibody, factor H-like 1 antibody, ARMS1 antibody, AHUS1 antibody, H factor 1 (complement) antibody, age-related maculopathy susceptibility 1 antibody, HUS antibody, HF antibody, factor H antibody, FHL1 antibody, complement factor H antibody, ARMD4 antibody, beta-1H antibody, adrenomedullin binding protein antibody, HF1 antibody, CFH antibody, CFHL3 antibody, HF2 antibody, beta-1-H-globulin antibody, complement factor H isoform b antibody, H factor 2 (complement) antibody, FH antibody, MGC88246 antibody, AMBP1 antibody |
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| Cross Reactivity | Human |
| Applications | WB |
| Immunogen | Complement factor H antibody was raised in rabbit using a synthetic peptide corresponding to a region within amino acids 527 and 618 of Complement factor H |
Images
Specifications
| Host | Rabbit |
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| Isotype | IgG |
| Method of Purification | Complement factor H antibody was purified by antigen-affinity chromatography |
| Molecular Weight | 139 kDa |
| Form & Buffer | Supplied as a concentrated soloution containing 1X PBS, 1% BSA, 20% Glycerol (pH 7.0). 0.01% Thimerosal was added as a preservative. |
| Concentration | 1 mg/ml |
Usage & Assay Information
| Usage Recommendations | WB: 1:1000-1:10000 |
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Storage & Safety
| Storage | Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
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General Information
| Biological Significance | This gene is a member of the Regulator of Complement Activation (RCA) gene cluster and encodes a protein with twenty short concensus repeat (SCR) domains. This protein is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in this gene have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. |
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