Complement factor H antibody (70R-12519)

Affinity purified Rabbit polyclonal Complement factor H antibody

Synonyms Polyclonal Complement factor H antibody, Anti-Complement factor H antibody, factor H-like 1 antibody, ARMS1 antibody, AHUS1 antibody, H factor 1 (complement) antibody, age-related maculopathy susceptibility 1 antibody, HUS antibody, HF antibody, factor H antibody, FHL1 antibody, complement factor H antibody, ARMD4 antibody, beta-1H antibody, adrenomedullin binding protein antibody, HF1 antibody, CFH antibody, CFHL3 antibody, HF2 antibody, beta-1-H-globulin antibody, complement factor H isoform b antibody, H factor 2 (complement) antibody, FH antibody, MGC88246 antibody, AMBP1 antibody
Cross Reactivity Human
Applications WB
Immunogen Complement factor H antibody was raised in rabbit using a synthetic peptide corresponding to a region within amino acids 527 and 618 of Complement factor H

Images

Immunohistochemical staining using Complement factor H antibody (70R-12519)

Immunohistochemical staining of paraffin-embedded U373 xenograft using Complement factor H antibody at a dilution of 1:200

Specifications

Host Rabbit
Isotype IgG
Method of Purification Complement factor H antibody was purified by antigen-affinity chromatography
Molecular Weight 139 kDa
Form & Buffer Supplied as a concentrated soloution containing 1X PBS, 1% BSA, 20% Glycerol (pH 7.0). 0.01% Thimerosal was added as a preservative.
Concentration 1 mg/ml

Usage & Assay Information

Usage Recommendations WB: 1:1000-1:10000

Storage & Safety

Storage Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance This gene is a member of the Regulator of Complement Activation (RCA) gene cluster and encodes a protein with twenty short concensus repeat (SCR) domains. This protein is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in this gene have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy.

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Images

  • <div><font face=Calibri size=2>Immunohistochemical staining using Complement factor H antibody (70R-12519)</font></div>     | Immunohistochemical staining of paraffin-embedded U373 xenograft using Complement factor H antibody at a dilution of 1:200
  • <div><font face=Calibri size=2>Western blot analysis using Complement factor H antibody (70R-12519)</font></div>     | Western blot analysis of 30 ug of whole cell lysate (A: Molt-4) using a 5 % SDS PAGE gel and Complement factor H antibody at a dilution of 1:5000

Availability: In stock

Price: €395.09
Size: 100 ul
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