Coronin 1a antibody (70R-10642)
Affinity purified Chicken polyclonal Coronin 1a antibody
Overview
Overview
| Synonyms | Polyclonal Coronin 1a antibody, Anti-Coronin 1a antibody, Coronin 1 alpha antibody, Coronin 1, Coronin -1 antibody, Coronin antibody, Coronin 1 antibody, Coronin 1, Coronin -1, Coronin 1 antibody |
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| Applications | ICC, IHC |
| Immunogen | Coronin 1a antibody was raised in Chicken using a synthetic peptide (Human NM_007074 and Mouse NM_009898) / keyhole limpet hemocyanin (KLH) conjugate corresponding to the Coronin gene product as the immunogen. |
Images
Immunofluorescent staining of Coronin 1a antibody (70R-10642)
Dissociated cell culture from a neonatal mouse brain showing Coronin 1a (green staining) of microglial cells. These cultures were counter-stained with rabbit antibodies against NFM (neurofilament, red staining), a neuronal marker, as well as DAPI (blue staining), a marker of nuclei. Picture courtesy of Dr. Gerry Shaw, University of Florida.
Specifications
| Host | Chicken |
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| Method of Purification | Coronin 1a antibody was purified by affinity chromatography. |
| Form & Buffer | Supplied in liquid form in 10 mM PBS buffer, pH 7.2, with 0.02% sodium azide added as a preservative. |
| Concentration | 100 ug/ml |
Usage & Assay Information
| Usage Recommendations | ICC: 1:1000-1:2000; IHC: 1:1000-1:2000 |
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Storage & Safety
| Storage | Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. Protect from light. |
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General Information
| Biological Significance | Coronin 1A may be a crucial component of the cytoskeleton of highly motile cells, functioning both in the invagination of large pieces of plasma membrane, as well as in forming protrusions of the plasma membrane involved in cell locomotion. In mycobacteria- infected cells, its retention on the phagosomal membrane prevents fusion between phagosomes and lysosomes. Belongs to the WD repeat coronin family. |
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