CRP antibody (10-2276)
Recombinant Fab monoclonal CRP antibody
Overview
Overview
| Synonyms | Monoclonal CRP antibody, Anti-CRP antibody, C-reactive protein antibody, C-reactive protein(1-205) antibody, C-reactive protein pentraxin-related antibody, CRP antibody, MGC149895 antibody, MGC88244 antibody, pentraxin 1 antibody, PTX1 antibody |
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| Specificity | Human |
| Protein Type | Recombinant |
| Applications | ELISA, Lateral Flow, Luminex Assay |
Specifications
| Host | Mouse |
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| Clone | M72059 |
| Isotype | IgG1 kappa - Fab fragment |
| Expression System | E.coli |
| Grade & Purity | > 95% pure |
| Method of Purification | CRP antibodies screened using Phage Display system. Expressed in and purified from E. coli. |
| Tag/Conjugate | His tag |
| Form & Buffer | Supplied as liquid in 50 mM Potassium Phosphate, 10 mM Boric Acid, 150 mM NaCl, pH 7 |
| Concentration | > 1 mg/ml |
Storage & Safety
| Storage | Store at -20 deg C in small aliquots. Avoid repeated freeze thawing. |
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General Information
| Biological Significance | CRP displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. CRP antibody was produced as a recombinant Fab monoclonal antibody in a Phage Display system. This anti-CRP antibody is used for detection of human CRP in ELISA, Lateral Flow, Luminex Assay. The concentration of the antibody ranges from 1 mg/ml to 25 mg/ml depending on the lot. Recombinant Fab monoclonal antibodies have a number of advantages over standard antibodies including; improved scale up for batch consistency, more efficient binding so less antibody required, more accurate binding meaning fewer conjugation issues, less non specific due to removal of the Fc region, more flexibility for purification and labeling through a C-terminal His tag. |
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